Ellansé Biostimulator Treatment
Restore Facial Volume and Stimulate Collagen for Natural-Looking Rejuvenation
Ellansé is a collagen-stimulating injectable treatment designed to restore facial volume while encouraging the skin's natural collagen production. At RJ Clinic, Ellansé can be considered for facial volume loss, skin laxity, wrinkles and age-related changes, with treatment tailored to your facial structure and aesthetic goals.
Last updated: 26 August, 2026 • Written by RJ Clinic Content Team • Reviewed by Dr. Renee Law
What Is Ellansé?
Ellansé is a collagen-stimulating injectable made with polycaprolactone (PCL) microspheres in a gel carrier. It is designed to provide an initial volumising effect while supporting collagen formation over time.
Unlike conventional hyaluronic acid (HA) fillers, which primarily work by adding volume through a gel, Ellansé works through both immediate volume and collagen stimulation. This makes it an option for patients looking to address facial volume loss while gradually improving the appearance of skin firmness and facial contours.
The suitability of Ellansé depends on factors such as your facial anatomy, skin condition, degree of volume loss and desired outcome. A doctor consultation is recommended before treatment.
Ellansé is a collagen-stimulating injectable containing polycaprolactone (PCL) microspheres in a gel carrier. It is designed to provide an initial volumising effect while supporting collagen formation over time. Clinical and scientific literature has examined the use of PCL-based collagen stimulators for facial volume augmentation and rejuvenation. [Read the PubMed review on Ellansé and PCL-based collagen stimulation.]
Ellansé contains polycaprolactone (PCL) microspheres, which are gradually broken down by the body over time.
After injection, the treatment can provide an initial volumising effect to help restore selected facial contours. As the PCL microspheres gradually resorb, they stimulate the body's collagen-producing response.
Over time, this collagen stimulation may help improve the appearance of skin firmness, facial structure and volume loss. The timing and extent of results vary between individuals and depend on factors such as age, skin condition, treatment area and the amount of product used.
How Does Ellansé Work?
What Does Ellansé Treat?
Ellansé may be considered as part of a personalised treatment plan for several signs of facial ageing and volume loss, including:
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Loss of facial volume
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Reduced cheek or mid-face definition
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Mild facial contour changes
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Fine lines and wrinkles
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Skin that appears less firm or elastic
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Age-related changes in facial structure
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Desire for gradual collagen stimulation alongside volume restoration
The treatment area and injection technique should be selected by a qualified doctor based on your facial anatomy and aesthetic goals.
Ellansé offers a different approach to facial rejuvenation by combining an initial volumising effect with collagen stimulation.
Immediate Facial Volume
Ellansé can provide an initial volumising effect after treatment, helping restore selected areas affected by facial volume loss.
Collagen Stimulation
The PCL component of Ellansé supports a gradual collagen-stimulating process, with changes developing over time.
Natural-Looking Facial Rejuvenation
When appropriately selected and placed, Ellansé can be used to restore facial structure while maintaining natural facial proportions.
Long-Lasting Results
The longevity of Ellansé results varies between individuals and depends on factors including the treatment area, product selection, injection technique and individual response.
Benefits of Ellansé
Who Is Suitable for Ellansé?
Ellansé may be suitable for adults who are concerned about facial volume loss, changes in facial contours, wrinkles or reduced skin firmness and are looking for a collagen-stimulating approach to facial rejuvenation.
You may wish to discuss Ellansé with a doctor if you are looking to:
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Restore selected areas of lost facial volume
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Improve facial contour and definition
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Address signs of age-related volume loss
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Support gradual improvement in skin firmness
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Achieve a refreshed appearance without surgical facial lifting
Not everyone is a suitable candidate for Ellansé. Your doctor will assess your medical history, facial anatomy, skin condition and treatment goals before recommending whether it is appropriate.
If your main concern is skin quality, hydration and the appearance of early skin ageing rather than facial volume loss, your doctor may recommend a different approach such as Belotero Revive for skin hydration.
Ellansé Treatment Process
1
Doctor Consultation
Your doctor will assess your facial structure, skin condition, volume loss and aesthetic goals. This helps determine whether Ellansé is suitable and which areas may benefit from treatment.
2
Treatment Planning
The doctor will develop an individualised treatment plan based on your facial anatomy and desired outcome. The amount and placement of Ellansé should be determined according to your individual needs.
3
Ellansé Injection
Ellansé is administered by injection into carefully selected areas. Treatment time varies depending on the number and location of areas being treated.
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Immediate Post-Treatment Period
Some patients may experience temporary redness, swelling, tenderness or bruising following the injections.
5
Follow-Up
A follow-up appointment may be recommended to assess your progress and determine whether any further treatment is appropriate.
Ellansé can provide an initial volumising effect following treatment, while collagen stimulation develops progressively over time.
The appearance of the treated area may continue to change as the collagen-stimulating process develops. Individual results vary depending on factors such as age, skin condition, treatment area, product selection, injection technique and individual response.
Ellansé results are not permanent, and the duration cannot be guaranteed for every patient. Your doctor can provide a more personalised expectation during consultation based on your treatment plan.
Collagen-stimulating treatments can produce changes progressively rather than immediately. If you would like to better understand how these treatments work and what factors can influence results, read our guide to understanding collagen biostimulator treatments before deciding on a treatment plan.
Ellansé Results: When Can You See Them and How Long Do They Last?
Ellansé Side Effects, Safety & Recovery
As with any injectable aesthetic treatment, Ellansé may cause temporary side effects. Common effects at or around the injection site can include:
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Redness
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Swelling
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Tenderness
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Bruising
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Mild discomfort
These effects are generally temporary, but recovery varies between individuals and treatment areas.
Because injectable treatments carry potential risks, Ellansé should only be administered following an appropriate medical assessment by a qualified practitioner. Your doctor will discuss the potential benefits, limitations and risks before treatment.
Follow the aftercare instructions provided by your doctor and contact the clinic if you experience symptoms that concern you after treatment.
As with other injectable aesthetic treatments, Ellansé may be associated with temporary reactions such as redness, swelling, tenderness or bruising. Published literature has also discussed the safety profile and potential adverse events associated with PCL-based collagen stimulators, highlighting the importance of appropriate patient assessment and injection technique. [View the scientific review on PCL collagen stimulators.]
Ellansé and traditional dermal fillers are not interchangeable treatments. The most suitable option depends on the patient's anatomy, skin condition and treatment goals.
Ellansé contains PCL microspheres and is designed to combine an initial volumising effect with collagen stimulation.
Hyaluronic acid (HA) fillers use hyaluronic acid gel to provide volume and contouring, with the product selected according to the treatment area and desired effect.
Your doctor may recommend one approach over another depending on whether your main concern is facial volume, contour definition, skin quality, or a combination of these factors.
Ellansé is one option for collagen stimulation and facial volume restoration. Depending on your facial structure and treatment goals, your doctor may also discuss other collagen biostimulator options such as Radiesse collagen biostimulator.
Ellansé vs Traditional Dermal Fillers
Why Choose Ellansé at Our Clinic?
Choosing the right practitioner is an important part of injectable treatment. At RJ Clinic, Ellansé treatment is planned according to each patient's facial anatomy, skin condition and aesthetic goals rather than using a one-size-fits-all approach.
Dr. Cheok is a regional trainer for Ellansé and provides training to doctors in injection techniques. This clinical experience supports RJ Clinic's approach to treatment planning, injection technique and patient safety.
Every Ellansé treatment begins with a doctor consultation to determine whether the treatment is appropriate and how it may fit into your overall facial rejuvenation plan.
We are proud to have Dr. Cheok, a regional trainer for Ellansé, on our team. Dr. Cheok ensures that we stay at the forefront of the most up-to-date injection methods and techniques, delivering maximum safety and exceptional results. With Ellansé, you can trust that you are receiving state-of-the-art treatment designed to rejuvenate your skin and enhance your natural beauty.
Treatment summary
Exceptional Quality
Procedure Time
45 minutes
Back to work
Immediate
Results
Immediate
Anesthetic
Numb cream provided
Downtime
Mild Swelling and redness for 1 week
Results Duration
2-3 years
What Our Clients Say
Frequently Asked Questions
Is Ellansé the same as a dermal filler?
Ellansé is a type of injectable collagen biostimulator with a volumising effect, but its mechanism differs from conventional hyaluronic acid fillers.
How long does Ellansé take to work?
An initial volumising effect may be visible following treatment, while collagen-related changes develop progressively. The timing varies between individuals.
How long does Ellansé last?
The duration of Ellansé results varies depending on individual factors, treatment area, product selection and other clinical factors. Your doctor can discuss expected longevity during consultation.
Is there downtime after Ellansé?
Temporary redness, swelling, tenderness or bruising may occur after treatment. Recovery varies depending on the individual and treatment area.
Is Ellansé suitable for everyone?
No. A medical consultation is necessary to determine whether Ellansé is appropriate based on your medical history, facial anatomy, skin condition and aesthetic goals.
